Crafting your own Cheeseburger Meatloaf is enjoyable and straightforward. Follow these steps to create a delicious masterpiece:

1. Preheat the Oven: Start by preheating your oven to 350°F (175°C).
2. Prep Baking Dish: Lightly grease a loaf pan or baking dish.
3. Mix Ingredients: In a large bowl, combine ground beef, breadcrumbs, milk, cheddar cheese, ketchup, mustard, onion, garlic, beaten egg, salt, black pepper, onion powder, garlic powder, and Worcestershire sauce.
4. Combine Thoroughly: Mix until all ingredients are well combined – your hands work best here!
5. Shape Meatloaf: Transfer the mixture to your loaf pan. Shape it into a loaf form, ensuring it fits well within the pan.
6. Top with Sauce: Spread an additional layer of ketchup and mustard on top, or your preferred sauces for flavor.
7. Bake: Place in the preheated oven and bake for approximately 1 hour, or until the meatloaf’s internal temperature reaches 160°F (70°C).
8. Rest: Once cooked, remove from the oven. Allow it to rest for 10-15 minutes. This step ensures the juices redistribute, making for a moist meatloaf.
9. Slice: After resting, slice into pieces, ensuring even portions for serving.
10. Garnish: Top with additional cheese or crispy fried onions if you desire.

These steps will guide you in creating an incredible Cheeseburger Meatloaf that will become a new family favorite.